Inkcazo eneenkcukacha
I-Chlamydia pneumoniae (C. pneumoniae) luhlobo oluqhelekileyo lwebhaktheriya kunye nonobangela omkhulu wenyumoniya kwihlabathi jikelele.Phantse i-50% yabantu abadala banobungqina bosulelo oludlulileyo ngeminyaka engama-20, kwaye ukuphinda usuleleke kamva ebomini kuyinto eqhelekileyo.Izifundo ezininzi zicebise unxulumano oluthe ngqo phakathi kosulelo lwe-C. pneumoniae kunye nezinye izifo ezivuthayo ezifana ne-atherosclerosis, ukunyanzeliswa kwe-COPD, kunye ne-asthma.Ukuxilongwa kosulelo lwe-C. pneumoniae lucelomngeni ngenxa yendalo ekhawulezayo ye-pathogen, i-seroprevalence enkulu, kunye nokuba nokwenzeka kwe-transient asymptomatic carriage.Iindlela zelebhu zokuxilonga ezisekiweyo zibandakanya ukwahlukaniswa kwento ephilayo kwinkcubeko yeeseli, uvavanyo lwe-serological kunye ne-PCR.Uvavanyo lwe-Microimmunofluorescence (MIF), "ngumgangatho wegolide" wangoku wokuxilongwa kwe-serological, kodwa uvavanyo lusanqongophele umgangatho kwaye luyingxaki yobuchwepheshe.I-Antibody immunoassays lolona vavanyo luqhelekileyo lwe-serology olusetyenziswayo kwaye usulelo oluphambili lwe-chlamydial lubonakaliswa yimpendulo ye-IgM ephambili kwiiveki ezi-2 ukuya kwezi-4 kunye nokulibaziseka kwe-IgG kunye ne-IgA impendulo kwiiveki ezi-6 ukuya kwezi-8.Nangona kunjalo, ekosulelweni kwakhona, amanqanaba e-IgG kunye ne-IgA anyuka ngokukhawuleza, rhoqo kwiiveki ezi-1-2 ngelixa amanqanaba e-IgM enokungafane afunyanwe.Ngesi sizathu, izilwa-buhlungu ze-IgA zibonise ukuba luphawu oluthembekileyo lwe-immunological losulelo oluphambili, olungapheliyo kunye nolwenzekayo ingakumbi xa ludityaniswe nokubhaqwa kwe-IgM.