Inkcazo eneenkcukacha
Indlela yokufumanisa i-syphilis
Ukufunyanwa kwe-antibody ye-Treponema pallidum IgM
Ukufunyanwa kwe-antibody ye-Treponema pallidum IgM yindlela entsha yokufumanisa igcushuwa kwiminyaka yakutshanje.I-antibody ye-IgM luhlobo lwe-immunoglobulin, enenzuzo yobuntununtunu obuphezulu, ukuxilongwa kwangaphambili, kunye nokuzimisela ukuba umntwana okhulelweyo wosulelwe yi-Treponema pallidum.Ukuveliswa kwezilwa-buhlungu ze-IgM ezithile yimpendulo yokuqala yomzimba yokuzikhusela emva kosulelo ngegcushuwa kunye nezinye iibhaktheriya okanye iintsholongwane.Ngokuqhelekileyo ilungile kwisigaba sokuqala sosulelo.Iyanda ngokukhula kwesi sifo, emva koko i-antibody ye-IgG inyuke kancinci.
Emva konyango olusebenzayo, i-antibody ye-IgM yanyamalala kwaye i-antibody ye-IgG yaqhubeka.Emva kokunyangwa kwe-penicillin, i-TP IgM yanyamalala kwinqanaba lokuqala izigulane ze-syphilis ezine-TP IgM positive.Emva konyango lwe-penicillin, izigulane ze-TP IgM ezine-syphilis yesibini zanyamalala phakathi kweenyanga ezi-2 ukuya kwezi-8.Ukongeza, ukufunyaniswa kwe-TP IgM kubaluleke kakhulu ekuxilongweni kwe-syphilis yokuzalwa kwiintsana.Ngenxa yokuba imolekyuli ye-antibody ye-IgM inkulu, i-antibody ye-IgM yoomama ayinakudlula kwi-placenta.Ukuba ngaba i-TP IgM ine-positive, umntwana wosulelekile.
Indlela yokufumanisa iSyphilis II
Ukufunyanwa kwebhayoloji yemolekyuli
Kwiminyaka yakutshanje, i-biology ye-molekyuli iphuhliswe ngokukhawuleza, kwaye iteknoloji ye-PCR isetyenziswe ngokubanzi kwiiklinikhi.I-PCR ebizwa ngokuba yi-polymerase chain reaction, oko kukuthi, ukukhulisa ulandelelwano olukhethiweyo lwe-spirochete DNA kwizinto ezikhethiweyo, ukwenzela ukwandisa inani leekopi ze-DNA ezikhethiweyo ze-spirochete, ezinokuthi ziququzelele ukufunyanwa kunye neeprobes ezithile, kunye nokuphucula izinga lokuxilonga.
Nangona kunjalo, le ndlela yovavanyo ifuna ilabhoratri eneemeko ezilungileyo ngokupheleleyo kunye neengcali zodidi lokuqala, kwaye zimbalwa iilabhoratri ezinenqanaba eliphezulu eTshayina okwangoku.Ngaphandle koko, ukuba kukho ukungcola, uya kubeka i-Treponema pallidum, kwaye emva kokukhulisa i-DNA, kuya kuba ne-Escherichia coli, ekwenza ube lusizi.Ezinye iikliniki ezincinci zihlala zilandela ifashoni.Baxhoma uphawu lwelabhoratri yePCR kwaye batye kwaye basele kunye, nto leyo enokuba kukukhohlisa.Enyanisweni, ukuxilongwa kwe-syphilis akufuni i-PCR, kodwa uvavanyo lwegazi jikelele.