Uvavanyo lweLegionella pneumophila Antigen

I-Legionnaires 'Diease, ebizwa emva kokuqhambuka kwe-1976 kwindibano ye-American Legion e-Philadelphia, ibangelwa yi-Legionella pneumophila kwaye ibonakaliswe njengesifo esibuhlungu sokuphefumla esisuka kubunzima ukusuka kwisigulo esincinci ukuya kwinyumoniya ebulalayo.Esi sifo senzeka kuzo zombini iifom zendyikityha kunye ne-endmic kwaye iimeko ezinqabileyo azihlulwa kalula kwezinye izifo zokuphefumla ngeempawu zeklinikhi.Kuqikelelwa ukuba i-25000 ukuya kwi-100000 yeemeko zosulelo lweLegionella zenzeka ngonyaka eUnited States.Izinga lokufa okubangelwayo, ukusuka kwi-25% ukuya kwi-40%, linokuthotywa ukuba isifo sifunyanwe ngokukhawuleza kwaye unyango olufanelekileyo lwe-antimicrobial luqaliswe kwangoko.Imiba eyaziwayo yomngcipheko ibandakanya ukugonywa komzimba, ukutshaya icuba, ukusetyenziswa kotywala kunye nesifo se-pulmonary concomitant.Abaselula nabakhulileyo ngabona basesichengeni.I-Legionella pneumophila ijongene ne-80% -90% yeemeko ezixeliweyo zosulelo lwe-Legionella kunye ne-serpgroup 1 ibalwa ngaphezu kwe-70% yazo zonke i-legionellosis.Iindlela zangoku zokufumanisa inyumoniya elabhoratri ebangelwa yiLegionella pneumophila zifuna umfuziselo wokuphefumla (umz. isikhohlela esine-expectorated, ukuhlamba i-bronchial, i-transtracheal aspirate, i-lung biopsy) okanye i-sera edityanisiweyo (ebukhali kunye ne-convalescent) ukuze kufunyaniswe uxilongo oluchanekileyo.

I-BESTest Legionella ivumela ukuxilongwa kwangaphambili kwe-Legionella pneumophila serogroup 1 infevtion ngokufumanisa i-antigen ethile enyibilikayo ekhoyo kumchamo wezigulane ezine-Legionnaires ' Disease.I-Legionella pneumophila serogroup 1 antigen ifunyenwe kumchamo kwangoko kwiintsuku ezintathu emva kokuqala kweempawu.Uvavanyo lukhawuleza, lunika iziphumo phakathi kwemizuzu eli-15, kwaye lusebenzisa umzekeliso womchamo olungele ukuqokelelwa, ukuthuthwa, kunye nokufunyanwa kwangaphambili, kunye nasemva kwexesha, izigaba zesifo.