Filariasis IgG/IgM Rapid Test Kit (Colloidal Gold)

I-lymphatic filariasis eyaziwa ngokuba yi-Elephantiasis, ngokuyintloko ebangelwa ngu-W. bancrofti no-B. malayi, ichaphazela abantu abamalunga ne-120 lezigidi kumazwe angaphezu kwama-80.Esi sifo sidluliselwa ebantwini ngokulunywa ziingcongconi ezosulelekileyo apho imicroflariae efunxayo kumntu owosulelekileyo ikhula ibe yimibungu yenqanaba lesithathu.Ngokuqhelekileyo, ukubonakaliswa okuphindaphindiweyo kunye nexesha elide kwimibungu esulelekileyo kuyafuneka ukuze kusekwe usulelo lomntu.

Uxilongo oluchanekileyo lweparasitologic lubonakaliso lwemicroflariae kwiisampulu zegazi.Nangona kunjalo, olu vavanyo lomgangatho wegolide luthintelwe yimfuno yokuqokelela igazi ebusuku kunye nokungabikho kovakalelo olwaneleyo.Ukufunyanwa kwee-antigens ezijikelezayo kufumaneka ngokurhweba.Ukusetyenziswa kwayo kulinganiselwe kwi-W. bancrofti.Ukongeza, i-microfilaremia kunye ne-antigenemia zikhula ukusuka kwiinyanga ukuya kwiminyaka emva kokuvezwa.

Ukufunyanwa kwe-antibody kunika iindlela zakwangoko zokubona usulelo lwe-filarial parasite.Ubukho be-IgM kwi-antigens ye-parasite bucebisa usulelo lwangoku, ngelixa, i-IgG ihambelana nenqanaba losulelo lwasemva kwexesha okanye usulelo oludlulileyo.Ngaphaya koko, ukuchongwa kwee-antigens ezigciniweyo kuvumela uvavanyo lwe-'pan-filaria' ukuba lusebenze.Ukusetyenziswa kweeprotheyini ezidibeneyo kuphelisa ukuhlangana kwabantu abanezinye izifo ze-parasitic.

I-Filariasis IgG/IgM Combo Rapid Test isebenzisa i-recombinant egciniweyo

ii-antigens zokubona ngaxeshanye i-IgG kunye ne-IgM kwi-W. bancrofti kunye ne-B. malayi parasites ngaphandle kwesithintelo ekuqokeleleni i-specimen.

I-Filariasis IgG/IgM Rapid Test Kit yi-lateral flow chromatographic immunoassay.I-cassette yovavanyo iqukethe: 1) i-burgundy colored conjugate pad equkethe i-recombinant W. bancrofti kunye ne-B. malayi i-antigens eqhelekileyo ehlanganiswe negolide ye-colloid (i-Filariasis conjugates) kunye ne-rabbit IgG-gold conjugates, i-2) i-nitrocellulose strip equkethe i-band band band (M) kunye ne-Mm kunye ne-band band yokuhlola (i-Mm kunye ne-band band yokuhlola)I-M band ifakwe ngaphambili kunye ne-monoclonal anti-human IgM yokuchongwa kwe-IgM anti- W. bancrofti kunye ne-B. malayi, i-G band ifakwe ngaphambili kunye nee-reagents zokubona i-IgG anti-W.bancrofti kunye B. malayi, kunye C band pre-uqatywe ngebhokhwe anti umvundla IgG.

Xa umthamo owaneleyo wesampulu yovavanyo ukhutshwa kwisampulu yequla lekhasethi, umzekelo ufuduka ngesenzo se-capillary kwikhasethi.W. bancrofti okanye B. malayi IgM antibodies ukuba zikhona kumzekelo ziya kubophelela Filariasis conjugates.I-immunocomplex ke ibanjwe kwi-membrane yi-anti-human IgM antibody, eyenza i-burgundy enemibala ye-M band, ebonisa i-W. bancrofti okanye i-B. malayi IgM isiphumo sovavanyo oluhle.

W. bancrofti okanye B. malayi IgG antibodies ukuba ikhona kwi-specimen iya kubophelela kwi-Filariasis conjugates.I-immunocomplex ke ibanjwe yi-reagents efakwe ngaphambili kwi-membrane, yenza i-burgundy enemibala ye-G band, ebonisa i-W. bancrofti okanye i-B. malayi IgG isiphumo sovavanyo oluhle.

Ukungabikho kwawo nawaphi na amabhanti ovavanyo (M no-G) ​​acebisa isiphumo esibi.Uvavanyo iqulathe ulawulo lwangaphakathi (C band) ekufuneka abonise band burgundy enemibala ye immunocomplex yebhokhwe anti umvundla IgG/umvundla IgG-igolide conjugate kungakhathaliseki ukuba uphuhliso umbala kuyo nayiphi na bands uvavanyo.Kungenjalo, iziphumo zovavanyo azisebenzi kwaye umboniso kufuneka uphinde uvavanywe ngesinye isixhobo.