Ulwazi olusisiseko
| Igama lemveliso | Ikhathalogu | Uhlobo | Umamkeli/uMthombo | Ukusetyenziswa | Usetyenziso | I-Epitope | I-COA |
| I-HCV Core-NS3-NS5 i-antigen ye-fusion | I-BMIHCV203 | I-Antigen | E.coli | Bamba | CMIA,WB | / | Khuphela |
| I-HCV Core-NS3-NS5 i-antigen ye-fusion | I-BMIHCV204 | I-Antigen | E.coli | Hlanganisa | CMIA,WB | / | Khuphela |
| I-HCV Core-NS3-NS5 fusion antigen-Bio | BMIHCVB02 | I-Antigen | E.coli | Hlanganisa | CMIA,WB | / | Khuphela |
| I-HCV Core-NS3-NS5 i-antigen ye-fusion | I-BMIHCV213 | I-Antigen | HEK293 Iseli | Hlanganisa | CMIA,WB | / | Khuphela |
I-pathogenesis ye-hepatitis C ayikacaci.Xa i-HCV iphindaphinda kwiiseli zesibindi, ibangela utshintsho kwisakhiwo kunye nomsebenzi weeseli zesibindi okanye iphazamise ukuhlanganiswa kweeprotheni zeseli zesibindi, ezinokubangela ukuhla kunye necrosis yeeseli zesibindi, ebonisa ukuba i-HCV iyonakalisa ngokuthe ngqo isibindi kwaye idlala indima kwi-pathogenesis.Nangona kunjalo, uninzi lweemathematika lukholelwa ukuba i-cellular immunopathological reaction inokudlala indima ebalulekileyo.Bafumanise ukuba i-hepatitis C, njenge-Hepatitis B, ine-CD3+engena iiseli ikakhulu kwizihlunu zayo.Iiseli ze-Cytotoxic T (TC) zihlasela ngokuthe ngqo iiseli ezijoliswe kuzo zosulelo lwe-HCV, ezinokubangela umonakalo weseli yesibindi.
I-RIA okanye i-ELISA
I-Radioimmunodiagnosis (RIA) okanye i-enzyme-linked immunosorbent assay (ELISA) yayisetyenziselwa ukufumanisa i-anti HCV kwi-serum.Ngowe-1989, uKuo et al.waseka indlela radioimmunoassay (RIA) for anti-C-100.Kamva, iNkampani ye-Ortho iphuhlise ngempumelelo i-enzyme-linked immunosorbent assay (ELISA) ukuze ibone i-anti-C-100.Zombini iindlela zisebenzisa igwele recombinant ibonakaliswe virus antigen (C-100-3, iproteni encoded yi NS4, equlathe 363 amino acids), emva kokucocwa, iqatywe ngenani elincinane imingxunya ipleyiti yeplastiki, kwaye yongezwa kunye neserum evavanyiweyo.I-antigen yentsholongwane idityaniswa ne-anti-C-100 kwi-serum evavanyiweyo.Okokugqibela, isotope okanye i-enzyme ebhalwe imouse anti human lgG monoclonal antibody iyongezwa, kwaye i-substrate yongezwa ukuzimisela kombala.
