Ulwazi olusisiseko
| Igama lemveliso | Ikhathalogu | Uhlobo | Umamkeli/uMthombo | Ukusetyenziswa | Usetyenziso | I-Epitope | I-COA |
| I-HEV Antigen | I-HEV Antigen | I-Antigen | E.coli | Bamba | CMIA, WB | / | Khuphela |
| I-HEV Antigen | BMIHEV012 | I-Antigen | E.coli | Hlanganisa | CMIA, WB | / | Khuphela |
| I-HEV Antigen | BMIHEV021 | I-Antigen | E.coli | Bamba | CMIA, WB | / | Khuphela |
| I-HEV Antigen | BMIHEV022 | I-Antigen | E.coli | Hlanganisa | CMIA, WB | / | Khuphela |
Indlela yosulelo lwe-hepatitis E (ikakhulukazi nge-fecal yomlomo) kunye nokubonakaliswa kwekliniki (usulelo olugqithileyo, i-hepatitis ebukhali, akukho hepatitis engapheliyo, njl.) zifana nezo ze-hepatitis A. Iziganeko ze-hepatitis E ziphezulu kubantu abatsha kunye nabantu abadala abaneminyaka eyi-15-39.I-Hepatitis E ikwasisifo esizimele.I-HEV nayo ayinayo i-pathological effect (CPE) kwi-hepatocytes.Umzimba unokufumana ukhuseleko oluthile emva kokugula, kodwa aluzinzanga ngokwaneleyo.Kukho isitofu sokugonya i-hepatitis E, kwaye amanyathelo okuthintela i-hepatitis E ikakhulu ibandakanya ukusika indlela yokudluliselwa komlomo we-fecal.
I-HEV ikhutshwa kwilindle lezigulana, isasazeke ngokudibana nobomi bemihla ngemihla, kwaye inokusasazwa okanye iqhambuke ubhubhane obangelwa kukutya okungcolisekileyo kunye nemithombo yamanzi.Incopho yezehlo idla ngokuba ngamaxesha emvula okanye emva kweempuphuma.Ixesha lokufukamela ziiveki ezi-2 ~ 11, kunye ne-avareji yeeveki ezi-6.Uninzi lwezigulana zeklinikhi ziphakathi ukuya kwi-hepatitis ephakathi, zihlala zizinciphisa, kwaye aziphuhli zibe yi-HEV engapheliyo.Ihlasela kakhulu abantu abadala abancinci, ngaphezulu kwama-65% abo bakwiqela leminyaka eyi-16 ukuya kwi-19 leminyaka ubudala, kwaye abantwana banosulelo oluncinci.
Inqanaba lokufa kwabantu abadala liphezulu kunelo le-hepatitis A, ngakumbi kubasetyhini abakhulelweyo abaphethwe yi-hepatitis E, kwaye izinga lokufa losulelo kwiinyanga ezintathu zokugqibela zokukhulelwa yi-20%.
Emva kosulelo lwe-HEV, inokuvelisa ukhuselo lomzimba ukukhusela i-HEV yosulelo kwakhona lohlobo olufanayo okanye iintlobo ezahlukeneyo.Kuye kwaxelwa ukuba i-anti-HEV antibody kwi-serum yezigulana ezininzi emva kokubuyiselwa kwimeko yesiqhelo ihlala iminyaka eyi-4-14.
Ukuxilongwa kovavanyo, amasuntswana entsholongwane anokufumaneka kwiindle nge-electron microscope, i-HEV RNA kwi-fecal bile ingabonwa yi-RT-PCR, kunye ne-anti HEV IgM kunye ne-IgG antibodies kwi-serum inokufunyanwa ngu-ELISA usebenzisa i-recombinant HEV glutathione S-transferase fusion protein njenge-antigen.
Uthintelo jikelele lwe-hepatitis E lufana nelo lwe-hepatitis B. Ii-immunoglobulins eziqhelekileyo azisebenzi kugonyo olungxamisekileyo.
