I-HCV(Ngokukhawuleza)

Uninzi lwezigulana azinazimpawu zicacileyo kwinqanaba elibukhali lokusuleleka, ehamba kunye namanqanaba aphezulu e-viremia kunye nokuphakama kwe-ALT.I-HCV RNA yavela egazini ngaphambi kwexesha kune-anti HCV emva kosulelo oluqatha lwe-HCV.I-HCV RNA inokufunyanwa kwiiveki ezi-2 emva kokuvezwa kwasekuqaleni, i-antigen engundoqo ye-HCV inokufunyanwa kwiintsuku ezi-1 ukuya kwezi-2 emva kokuba i-HCV RNA ibonakala, kwaye i-anti-HCV ayinakubonwa kude kube kwiiveki ezisi-8 ukuya kwezi-12, oko kukuthi, emva kokusuleleka kwe-HCV, kukho malunga neeveki ezi-8-12, kuphela i-HCV RNA inokufunyanwa i-anti, ngelixa i-HCV ingabonakali, ngelixa "i-HCV" ixesha lefestile” linxulumene nesixhobo sokubhaqa (jonga iTheyibhile 1).I-Anti HCV ayilo-antibody ekhuselayo, kodwa luphawu losulelo lwe-HCV.I-15% ~ 40% yezigulane ezinosulelo olubukhali lwe-HCV zinokususa usulelo kwiinyanga ezi-6.Kwinkqubo yokucoca usulelo, inqanaba le-HCV RNA linokuba liphantsi kakhulu ukuba lingabonwa, kwaye kuphela i-anti HCV efanelekileyo;Nangona kunjalo, i-65% ~ 80% yezigulane azizange zisuswe kwiinyanga ezi-6, ezibizwa ngokuba yi-HCV engapheliyo.Emva kokuba i-hepatitis C engapheliyo isenzeka, i-HCV RNA titer iqala ukuzinza, kwaye ukuchacha ngokuzenzekelayo kunqabile.Ngaphandle kokuba unyango lwe-antiviral olusebenzayo lwenziwa, ukucocwa okuzenzekelayo kwe-HCV RNA kunqabile ukuba kwenzeke.Kwinkqubo yezonyango, uninzi lwezigulana ezine-hepatitis C ezingapheliyo zilungile kwi-anti HCV (izigulane ezi-immunosuppressed, ezifana nezigulana ezine-HIV, abamkeli bokufakelwa kwelungu eliqinileyo, izigulane ezine-hypogammaglobulinemia okanye izigulane ze-hemodialysis zinokuba zibi kwi-anti-HCV), kunye ne-HCV RNA inokuthi ibe ntle okanye ingabikho (inqanaba le-HCV RNA liphantsi emva konyango lwe-antiviral).